In this blog post, Dr. Lanay Mudd describes NIH initiatives designed to enhance the accountability and transparency of clinical research.
NCCIH Research Blog
Blog Posts Category
NCCIH blogs about research developments related to complementary health practices. Check in regularly to keep up with the latest findings.
In this blog post, NCCIH Training Officer Dr. Lanay Mudd discusses research training and career development opportunities.
In this blog post Dr. Merav Sabri discusses funding opportunities for small businesses – the Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) programs.
In this research blog, Drs. Robin Boineau (NCCIH) and Kimberly Johnson (SAMHSA) discuss a new funding initiative to examine the impact of behavioral interventions for opioid addiction within the context of states’ plans for use of Opioid STR grant funds.
In this blog post, Dr. Catherine Meyers discusses The Living Textbook, a researcher-friendly compendium of information for designing, planning, and implementing pragmatic clinical trials.
I am proud to announce NIH’s newest interagency research initiative on pain management in military service members and veterans.
NCCIH, lead for this multi-agency initiative called the NIH-DoD-VA Pain Management Collaboratory, is contributing more than half the funding for these 12 projects to develop, implement, and test nondrug approaches for managing pain and its related conditions in the military and veteran population―including opioid misuse, abuse, and disorder. The total funding for this project will be $81 million over 6 years.
In this blog post, Dr. Craig Hopp discusses NCCIH’s focus on natural products research.
Illnesses and deaths linked to tobacco smoking are a huge public health problem in the United States and worldwide. Although treatments such as counseling and medication are available to help people stop smoking, research indicates that these treatments are not always available or successful for every patient, and that an individualized approach is desirable.
In this blog post, NCCIH Director of Extramural Research Dr. Emmeline Edwards discusses NIH/NCCIH funding opportunities in music and art therapies.
Find out more about a new series of funding opportunity announcements for investigator-initiated clinical trials, and register for this May 9 webinar: New NCCIH Funding Opportunities for Natural Products Clinical Trials.
NCCIH to host informational webinars in April and May, 2017, on clinical trial applications via new funding opportunities.
In this blog post. NCCIH Director Dr. Josephine Briggs discusses NCCIH partnerships to research military/veteran health and how clinical practice guidelines affect research.
Probiotics researcher Dr. John Cryan lecture is the subject of an online CME lecture titled “Towards Psychobiotics: The Microbiome as a Key Regulator of Brain and Behavior.”
Today, NCCIH grantee Dr. Christina Smolke from Stanford University will present her innovative research at the 2016 High-Risk, High-Reward Research Symposium at NIH. Her team’s successful engineering of a yeast strain capable of making opioids was lauded in both Science and Nature in 2015.
In this blog post, Dr. Partap Khalsa welcomes applicants for a program director position in the NCCIH Division of Extramural Research’s Basic and Mechanistic Research Branch.
Over the years, I have often been asked whether the National Center for Complementary and Integrative Health (NCCIH) will fund clinical trials of natural products. The answer is, “Yes.” NCCIH funds clinical research of natural products, including herbal products, botanicals, products marketed as dietary supplements, and probiotics.
In this research blog post,
Join NCCIH’s Division of Extramural Research as a Program Director to drive investigations to better understand the human microbiome.
In this blog post, Dr. Eve Reider discusses NCCIH initiatives that may help determine if and how complementary and integrative health approaches may contribute to disease prevention and health promotion across the lifespan.
In this blog post, Dr. Craig Hopp speaks to the necessity of using high-impact research approaches to uncover the biological signatures of complex natural products.
In this blog report, Dr. Wen Chen talks about NCCIH objectives for research on neurobiological effects and mechanisms.
In this blog post, Dr. Partap Khalsa talks about NCCIH’s priorities for pain research, such as managing chronic pain via non-drug means.
NCCIH Director Dr. Josephine Briggs announces and outlines the Center’s 2016 Strategic Plan.
In this blog post, Dr. Emmeline Edwards offers advice on NIH funding opportunities and mechanisms, and discusses the NCCIH-sponsored session on funding opportunities at the upcoming 2016 ICIMH meeting.
In this blog post, Dr. Partap Khalsa discusses NCCIH priorities for pain research and highlights promising avenues of investigation.
In this blog post, Dr. Emmeline Edwards discusses NCCIH priorities in pain and pain management research, & highlights NCCIH involvement at the 2016 American Pain Society’s annual meeting.
In this blog post, Dr. Wen Chen discusses the need for mechanistic research in clinical studies.
In this blog post, Dr. Wendy Weber talks about an upcoming session at the International Congress on Integrative Medicine and Health (ICIMH) that deals with what NCCIH is looking for in clinical research applications.
In this blog post, Dr. John Williamson of NCCIH’s Division of Extramural Research talks about two projects that have received NCCIH funding via SBIR grants.
This blog post announces the upcoming NIH event: “Marijuana and Cannabinoids: A Neuroscience Research Summit” to be held March 22-23, 2016.
In this blog post, Dr. Partap Khalsa reports on the National Advisory Council for Complementary and Integrative Health Working Group on Clinician-Scientist Workforce Development.
SROs are scientists, most are former faculty members and NIH grantees, who manage the first level of peer review, commonly known as the study section. SROs are the people who take the first thorough look at your application, determine the expertise required for the review, recruit the external scientists to match that expertise, manage the study section meeting where the applications are discussed and scored, and prepare the summary statement for your application.
In this blog post, NCCIH scientist Ashlee Tipton discusses compiling a list of natural product libraries on the NCCIH website.
New RFAs represent NCCIH’s new funding mechanisms direct research attention toward investigating the mechanisms by which: 1) mind and body interventions might work, and 2) strategies to optimize these interventions.
Dr. Craig Hopp announces NCCIH’s grant for a new Center of Excellence for Natural Product Drug Interaction Research in this blog post.
NCCIH priorities in pain research and cutting-edge pain management research will be presented at the upcoming 2015 American Pain Society (APS) meeting, as Dr. Emmeline Edwards explains in this blog post.
In this blog post, NCCIH Branch Chief Dr. Wendy Weber describes the use of the R34 funding mechanism for early stages of clinical research on mind and body interventions.
NCCAM Director Dr. Josephine Briggs discusses the role of integrative medicine in symptom management in cancer survivors in this blog post.
In this blog post, Dr. Kristen Huntley describes a new research initiative on nondrug approaches to pain and related conditions in U.S. military personnel and veterans.
In this blog post, NCCAM Deputy Director Dr. David Shurtleff talks about NCCAM’s role in President Obama’s Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative.
In this blog post, NCCAM statistician Barbara Stussman discusses the 2012 National Health Interview Survey (NHIS), which asked about Americans’ use of complementary and alternative medicine..
I have an exciting new funding opportunity announcement (FOA) to tell you about: the “Center for Advancing Natural Products Innovation and Technology (U41),” or RFA-AT-14-006. This grant is part of a diverse portfolio of projects on natural products research cosponsored by NCCAM and the NIH Office of Dietary Supplements (ODS). The goal of this FOA is to improve upon and strengthen the technologies and methods used in natural-products research—leading to better understanding of the biology and chemistry of natural products and how they impact health and wellness.
Earlier this week, a new secondary analysis of results of the Trial to Assess Chelation Therapy (TACT) was published in the journal Circulation: Cardiovascular Quality & Outcomes and presented at the American Heart Association meeting. The analysis suggests that the EDTA-based chelation treatments produced a marked reduction in cardiovascular events and death in participants with diabetes. Furthermore, the results suggest that treatments had no benefit in those who did not have diabetes.
Chronic low-back pain is one of the most common and costly health complaints. It can be debilitating, and it remains a tough condition to diagnose, treat, and study. Spinal manipulative therapy is often used to treat a large portion of low-back pain in the United States, and is included in current clinical practice guidelines for treatment of this condition. Yet, recommendations for duration and frequency vary widely and there is no consensus on its efficacy.
Two winters ago, I was skiing at a local ski area and became intrigued by an activity I saw there. Two groups—Wounded Warrior Project and Two Top Mountain Adaptive Sports Foundation—were on the mountain that day. They sponsor programs to help wounded service members find ways, through adaptive sports, to ease back into active lives.
Summer 2013 marks the first anniversary of Dr. Catherine Bushnell’s appointment as Scientific Director of NCCAM’s Division of Intramural Research. You can find out more about Dr. Bushnell and the Division here. The blog team asked Dr. Bushnell for a few reflections on her first year at NCCAM.
The first year of the new NCCAM intramural pain research program has been a great success.
Today, Liz Szabo of USA Today offers a thoughtful look into the field of complementary and alternative health. Szabo cites cautionary tales of unfounded health claims and aggressive marketing come-ons that can be common. Yet, she makes room for another critical point—a number of complementary health practic
As we know, chronic low back pain (cLBP) is an enormous public-health problem—and a frustrating one to patients, health-care providers, and researchers. Up to one-quarter of Americans experience LBP per year, and for some, that pain becomes chronic—a condition that costs the United States an estimated $100 billion per year. Current best practices for its diagnosis and treatment are only partially successful.
In my talks to the scientific community, I often stress the importance of basic and translational research in creating a foundation for definitive clinical investigation. Developing insight into physiological effects and mechanism of action is critical to the scientific evidence base that guides clinical practice and public use, and it has the significant potential to inform other fields of biomedical research. I am pleased that NCCAM is supporting such important research.
In addition to funding research at academic institutions, the National Institutes of Health supports research by small businesses throughout the United States. The Small Business Innovation Research (SBIR) program and the Small Business Technology Transfer (STTR) program are two programs established by Congress to support small businesses and commercialization of federally funded research.
Two years ago, in February 2011, we released NCCAM’s Third Strategic Plan. The plan articulated our Center’s goals and objectives and presented a structure for determining priorities for future research. As we greet this anniversary, I’m pleased to report that we are successfully putting the plan into action.
The U.S. population is a rapidly aging one. In the coming years, many, if not most of us, will face changes and challenges—in our family members, friends, and/or ourselves—related to health problems that occur with aging. These include dementia, which, although not a normal part of aging, is common in very elderly people. One problem that is sometimes overlooked in considering the burdens of dementia is its effects on the health of family members who assume the burdens of care. We are proud to be supporting several studies of interventions that aim to help caregivers.
NCCAM has supported a fair number of studies on the potential health benefits of yoga. Of particular interest has been exploring the role of yoga as a strategy for alleviating symptoms such as chronic pain or stress or for promoting healthier lifestyles. There is still a lot we don’t know, but there is a growing body of clinical research evidence that now suggests that yoga can enhance quality of life, reduce psychological stress, and improve some mental health outcomes.
Recently, six of NCCAM’s outstanding natural products research grantees were invited to present posters following the 2012 Stephen E. Straus Distinguished Lecture in the Science of Complementary Health Therapies delivered by David Kingston, Ph.D. Their research presentations were a small sample of the importance and scientific merit of natural products research supported by NCCAM, and they complemented Dr. Kingston’s talk.
We are planning a series of blog posts to highlight some exciting work from our research portfolio. Research we support has led to more than 3,000 peer-reviewed papers; hundreds are published each year. We plan to highlight a few here, choosing examples that illustrate both the promise and the challenges of research on complementary health practices.
In 2005, the Institute of Medicine called for the National Institutes of Health to “implement periodic comprehensive, representative, national surveys to assess the changes in the prevalence, patterns, perceptions, and costs of [complementary] therapy use…”.
The July 16 issue of the Medical Journal of Australia (MJA) published an editorial addressing the debate as to whether complementary medicine courses should be taught in Australian universities. In many ways, the debate in Australia parallels debates here in the United States, and indeed debates on this blog.
This past month my daughter gave me a set of meditation CDs for mother’s day, and I have begun to put them to good use—but I have to admit that it has not been all that easy to quiet my brain and be in “a state of mind cultivated by paying attention on purpose, deeply, and without judgment to whatever arises in the present moment, either inside or outside of us.” Not one to give up easily, I have continued my 20 minutes of meditation practice daily but as a neuroscientist, I would really love to better understand what goes on in my brain during these sessions&he
Two weeks ago was the occasion of the NIH Pain Consortium 7th Annual Symposium on Advances in Pain Research. It was a great meeting, and we heard some terrific science presented. Modern neuroscience is clearly opening up our understanding of how the brain processes painful stimuli, and is yielding insights about how emotional states (or even placebo pills) modify the processing of pain in the brain.