An official website of the United States governmentNatural Product Libraries
This listing is for informational purposes only and is not a comprehensive listing. The National Center for Complementary and Integrative Health (NCCIH) does not guarantee the availability or content of any of the listed libraries. Acceptance of any such terms is at the sole discretion of the prospective user, and as agreed to between the prospective user and the library administrator. Inclusion on this listing does not indicate NCCIH’s approval of such terms, and does not constitute an endorsement or recommendation of any specific commercial products, process, service, manufacturer, or company by the U.S. Government, or specifically by the National Institutes of Health or NCCIH.
| Library Name and/or Company | Contact Information | Materials Available in the Library | Information About the Materials |
|---|---|---|---|
| AnalytiCon Discovery | ac-discovery.com 240-406-1256 d.wolf@ac-discovery.com | Natural compounds from microbial and terrestrial sources | Information not provided for listing; consult with company. |
| Axxam/AXXSense | sara.santangelo.ss@axxam.com info@axxam.com | Comprehensive access to nature’s chemical diversity: plants, fungi, microbial strains (11,500 pure natural compounds derived from plant and microbial sources; 63,000 purified fractions derived from distinct microbial extracts; 21,200 pre-purified extracts including samples derived from microbial extracts, plants and mushroom fruit bodies; 40,000 distinct strains from bacterial and fungal genetic sources) | Information not provided for listing; consult with company. |
| BioAustralis | bioaustralis.com +61-2-9757-4515 info@bioaustralis.com | High purity metabolites from bacteria and fungi | Product name, synonym, CAS number, molecular formula, molecular weight, description of chemical, and biological characteristics |
| Biosortia Microbiomics | biosortia.com 614-573-1903 chummell@biosortia.com | Biosortia makes available rare small molecules (SMs) made from microorganisms (bacteria, fungi, archaea, and viruses) in natural microbiomes. We specialize in the “hard to obtain” or large quantities by special request for rare SMs. | Chemical structures and biological activities of the compounds are available. |
BOC Sciences
| 1-631-504-6093 | More than 6,000 purified natural products extracted from microorganisms or plants. | Product name, alternative names, CAS number, molecular formula, molecular weight, description, natural sources, and reference information are provided. |
| Caithness Biotechnologies, Phytotitre Natural Product Library | caithnessbiotechnologies.com
| Unique focus on plants with a history of use as traditional medicines or association with reduced risk of disease in studies of dietary epidemiology aims to maximize accessibility and hit rate for groups seeking to screen natural product libraries. 800 extracts in DMSO, microplate format. | Information on traditional ethnomedicinal use or other rationale for inclusion in the library is provided in electronic format with plate maps. |
| ChemBioFrance | chembiofrance.cn.cnrs.fr/en/ contact@chembiofrance.org | More than 15,000 natural extracts from plant, animal, marine, and microbial sources. | The natural extract library is available for screening in frozen 96-well plates, in standard solutions (DMSO, 10 mg/ml). |
| ChromaDex Natural Compound Libraries | chromadex.com/standards/natural-product-libraries 949-419-0288 sales@chromadex.com | Wide selection of high-quality reference standards suited for the natural products industry focusing on dietary supplements, food and beverage, skin care, and pharmaceutical markets. Has been developed with a key balance of known active and well-characterized phytochemicals in combination with unusual and difficult-to-isolate compounds. | Neat inventory immediately available. Botanical extract library, produced through a proprietary extraction process combining both serial and parallel techniques to decrease false negatives and maximize screening hits; 1,200 are extensively characterized; 2,550 total fractions; derived from 425 plants and plant parts; cross-fraction synergy preserved. |
| Curia | curiaglobal.com/small-molecules/discovery/ 877-275-2674 go.curiaglobal.com/curia-contact-us.html | Samples derived from marine and terrestrial microorganisms and plants | Information not provided for listing; consult with company. |
| Cyano Biotech | cyano-biotech.com/content/biomasstocompounds +49-0-30-63924481 +49-0-30-63924489 info@cyano-biotech.com | Natural products from cyanobacteria | Libraries in the form of crude extracts, prefractionated extracts, and pure compounds in 96 well MTPs ready to screen. Bioactivity data for all library formats available on request. |
| Developmental Therapeutics Program, the National Cancer Institute Natural Products Repository, National Institutes of Health | dtp.cancer.gov/organization/npb/introduction.htm ncidtpinfo@mail.nih.gov | One of world’s most comprehensive collections of natural products. More than 230,000 crude extracts from plant, marine and microbial sources from countries around the world; over 400 purified natural product compounds; traditional Chinese medicinal plant extracts library. | No cost for materials; only shipping fee is charged; in both 96- and 384-well formats ready for HTS screens. |
| Greenpharma Natural Compound Library | greenpharma.com/products/compound-librairies/#GPNCL +33-0-238-259-980 info@greenpharma.com | Diverse and pure compounds from natural resources including plants, bacteria and other terrestrial sources | Electronic file containing the structure, the name, the position of each product in the microplate, examples of natural sources producing the compounds, and calculated physico-chemical descriptors |
| INDOFINE Chemical Company | indofinechemical.com Sujata Moton 908-359-6778 121 Stryker Lane Hillsborough, NJ 08844 chemical@indofinechemical.com | Offers natural products, herbal and nutritional products, flavonoids, and coumarins. Can make a custom library. | All of the natural products are extracted. Products are of high purity. |
| InterBioScreen | screen@ibscreen.com | Synthetic and natural compounds and their derivatives. Synthetic compounds with maximal diversity and natural compounds isolated from various natural sources such as plants, fungi, molds, insects, marine organisms, or produced by total synthesis of natural products and/or derivatives of natural products obtained by their chemical modification. | Information not provided for listing; consult with company. |
| InterLink Biotechnologies | interlinkbiotech.com/natural-products.html rlgarcia@interlinkbiotech.com 609-933-3798 | More than 200,000 microbial and plant extracts (fractions available), purified compounds, and microbial strains from large and diverse sources | Information not provided for listing; consult with company. |
| Magellan BioScience | magellanbioscience.com/libraries/index.html 813-623-6800 info@magellanbioscience.com | Marine microbes from sediment water and associated invertebrate and plant tissues | Information not provided for listing; consult with company. |
| MedChemExpress | medchemexpress.com/screening-libraries.html 609-228-6898 sales@medchemexpress.com | Purified natural products sourced from plant, animal, marine and microbial sources, as well as natural product synthetic equivalents for research | A unique collection of 3500+ natural products and natural product synthetic equivalents encompassing saccharides, glycosides, phenylpropanoids, quinones, flavonoids, terpenoids, steroids, alkaloids, phenols, acids and aldehydes. All natural products have clear sources and structural classifications. Detailed information include product name, CAS number, structure, formula weight, source type, structure type, solubility, SMILES, biological activity, clinical information, etc. |
| MEDINA | medinadiscovery.com +34 958 993 965 info@medinaandalucia.es | One of the world´s largest libraries of microbial-derived natural products. More than 200,000 extracts from marine and terrestrial microorganisms from the most diverse environments all around the world. | The library is organized in modules robotically integrated for faster and efficient screening and is available for testing at MEDINA or at external partner site. |
| MicroSource Discovery Systems | msdiscovery.com/natprod.html 860-350-8078 compounds@msdiscovery.com | Approximately 75% of the collection encompasses: alkaloids (16%), flavanoids (12%), sterols/triterpenes (12%), diterpenes/sesquiterpenes (10%), benzophenones/chalcones/stilbenes (10%), limonoids/quassinoids (9%), and chromones/coumarins (6%). The remainder of the collection includes quinones/quinonemethides, benzofurans/benzopyrans, otenoids/xanthones, carbohydrates, and benztropolones/depsides/depsidones. | Collection of 800 compounds, all are fully characterized according to literature reports and meet criteria of a minimum of 95% purity. Compounds selected on the basis of structural and chemical class. |
| Natural Product Discovery Center, Scripps Research | scripps.edu/shen/natural-product-discovery-center/ 561-228-2456 shenb@scripps.edu | Natural products of bacterial origin, as MPLC fractions and crude extracts | Structures of the pure compounds, HPLC chromatograms of the fractions and extracts, geographic location and ecological environment of the strains from which the fractions and crude extracts were prepared, and very limited activity information associated with them |
| Natural Products Discovery Core, University of Michigan | lsi.umich.edu/science/centers-technologies/natural-products-discovery-core 734-647-7772 natprodcore@umich.edu | Metadata enabled (chemical and genetic profile) 45,000 NPEs (and still growing) from diverse marine/terrestrial actinomycetes | NPEs from Asia-Pacific, the Middle East, North and South America, and the Antarctic. The library is configured in HTS format (94/384/1536 well) for scientific exploration (academia/industry). Internal HTS facility, Center for Chemical Genomics. |
| NatureBank, Griffith Institute for Drug Discovery, Griffith University | griffith.edu.au/institute-drug-discovery/unique-resources/naturebank Rohan Davis r.davis@griffith.edu.au | Marine- and plant-derived lead-like enhanced extract (>18,000), fraction (>90,000) and pure compound (>100) libraries | Samples have been processed into three unique libraries: a lead-like extract library, a lead-like fraction library, and a pure compound library, which are ready for screening to discover new bioactive compounds in a range of applications (e.g., biomedical, agrochemical, nutraceutical). Also holds more than 30,000 archived biota samples. These libraries represent the unique biodiversity of Australia, which translates into novel chemical diversity. |
| Quality Phytochemicals | qualityphytochemicals.com 908-510-9277 sales@qualityphytochemicalsllc.com | Natural compounds/phytochemicals for research | Information not provided for listing; consult with company. |
| Selleck Chemicals | selleckchem.com/screening/natural-product-library.html 877-796-6397 (U.S. and Canada only) 832-582-8158 sales@selleckchem.com | Purified natural products for research | A unique collection of 2,228 natural products for high-throughput screening and high-content screening. Includes quinones, flavonoids, terpenoids, alkaloids, saponins, medicine food homology compounds, human endogenous metabolite compounds and natural organic compounds. Structurally diverse, bioactive, and cell permeable; rich documentation with structure; NMR and HPLC validated ensure high purity. |
| Specs | specs.net 401-782-2994 david.hayes@specs.net | Purified natural products and derivatives thereof from natural sources like plants, fungi, bacteria, and sea organisms | Molecular structure and molecular formula, name of the natural product (if the compound is a derivative, the name of the parent structure and “derivative of” is mentioned, e.g., “dubamine derivative of”), name of the source of the natural product (e.g., “isolated from haplophullum latifolium”), and available stereochemical information |
| TargetMol Chemicals, Inc. Natural Product Library for HTS | https://www.targetmol.com/all-compound-libraries 781-999-4286 inquiry@targetmol.com | Purified natural products sourced from plant, animal, microorganism, marine species, etc. The collection of this library encompasses alkaloids, flavonoids, glycosides, phenols, phenylpropanoids, quinones, saccharides, steroids, and terpenoids. | A unique collection of 4,533 compounds with highly customizable option for high-throughput screening and high-content screening. Detailed information including product name, molecular structure, CAS number, molecular formula, molecular weight, source, bioactivity, status, and trade name. |
| TimTec | timtec.net/natural-compound-library.html 302-292-8500 info@timtec.net | Compounds sourced from plants, bacteria, fungus, and animals | Common natural sources and reference information is available for natural product library records. |
Please send all requests for inclusion of new libraries and any changes in information for libraries currently listed to Dr. Craig Hopp. Submissions should be limited to a word count of 50 or less.