Fenugreek
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Common Names: fenugreek
Latin Names: Trigonella foenum-graecum
Background
- Fenugreek is a clover-like herb native to the Mediterranean region, southern Europe, and western Asia. Its seeds, which smell and taste like maple syrup, have been used as a spice and a traditional medicine. Because of its maple-like flavor, fenugreek has been used as a flavoring agent in foods, beverages, and tobacco.
- Fenugreek has been used as a medicinal plant for about 6,000 years. In various cultures, it has been used as a tonic or a laxative; as a remedy for menstrual cramps, menopause symptoms, kidney stones, and other conditions; and to stimulate milk production during breastfeeding.
- Today, fenugreek seed is promoted as a dietary supplement for diabetes, menstrual cramps, and many other conditions and to stimulate milk production during breastfeeding.
How Much Do We Know?
- There is not enough high-quality evidence to determine whether fenugreek is useful for diabetes or menstrual cramps.
- A few studies have evaluated the use of fenugreek to increase milk supply in breastfeeding women, with mixed results. More high-quality studies are needed before conclusions can be reached about fenugreek’s effects on these conditions.
- Fenugreek is not safe for use during pregnancy in amounts greater than those found in food; its use has been linked to increased risks of birth defects.
What Have We Learned?
- Research has suggested that fenugreek may help lower blood sugar levels in people with type 2 diabetes, but many of the studies were not of high quality.
- Only a small number of studies have examined the effect of fenugreek on menstrual cramps. The evidence is of low quality, and the effects of fenugreek on this condition are uncertain.
- It’s uncertain whether fenugreek can increase milk supply in breastfeeding women; studies have had mixed results.
- The evidence on fenugreek for other health conditions is too limited for any conclusions to be reached.
What Do We Know About Safety?
- Fenugreek is believed to be safe for adults and children in the amounts commonly found in foods. It is possibly safe for adults in larger amounts. There is not enough information to say whether it is safe for children to take fenugreek in amounts larger than those found in foods.
- Potential side effects of fenugreek include diarrhea, nausea, and other digestive tract symptoms. Large doses may cause a harmful drop in blood sugar. Fenugreek can cause allergic reactions, including serious reactions, in some people.
- If you take any type of medicine, talk with your health care provider before using fenugreek or other herbal products; some herbs and medicines interact in harmful ways.
- Fenugreek is not safe for use during pregnancy in amounts greater than those found in food; its use has been linked to increased risks of birth defects in both animals and people.
- Little is known about whether it’s safe to use fenugreek in amounts greater than those found in food while breastfeeding.
Keep in Mind
- Take charge of your health—talk with your health care providers about any complementary health approaches you use. Together, you can make shared, well-informed decisions.
- Federal Regulation of Herbal Products
- Depending on what’s in them, how they’re intended to be used, and how they’re administered (orally or topically), herbal products are regulated in a variety of ways. Many herbal products intended for oral use are marketed as dietary supplements. The rules for making and distributing dietary supplements are less strict than those for drugs.
- Unlike drugs, dietary supplements are not approved by the U.S. Food and Drug Administration (FDA) before they are sold to the public. When public health concerns arise about the safety of a dietary supplement or an ingredient including an herb, the FDA can take action to protect the public. Manufacturers and distributors of supplements are responsible for evaluating the safety and labeling of their products before marketing to ensure that they meet all regulatory requirements.
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Key References
- Bernstein N, Akram M, Yaniv-Bachrach Z, et al. Is it safe to consume traditional medicinal plants during pregnancy? Phytotherapy Research. 2021;35(4):1908-1924.
- Fenugreek. Drugs and Lactation Database. (LactMed). National Institute of Child Health and Human Development. Updated September 2023. Accessed at ncbi.nlm.nih.gov/books/NBK501779 on October 19, 2023.
- Fenugreek. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. National Institute of Diabetes and Digestive and Kidney Diseases. Updated January 29, 2018. Accessed at ncbi.nlm.nih.gov/books/NBK548826 on October 19, 2023.
- Fenugreek. NatMed Pro website. Accessed at naturalmedicines.therapeuticresearch.com on October 19, 2023. [Database subscription].
- Foong SC, Tan ML, Foong WC, et al. Oral galactagogues (natural therapies or drugs) for increasing breast milk production in mothers of non-hospitalised term infants. Cochrane Database of Systematic Reviews. 2020;(5):CD011505. Accessed at cochranelibrary.com on October 19, 2023.
- Forci K, Bouaiti EA, Alami MH, et al. Incidence of neural tube defects and their risk factors within a cohort of Moroccan newborn infants. BMC Pediatrics. 2021;21(1):124.
- Hassanzadeh R, Shabani F, Montazeri M, et al. The effect of fenugreek on the severity of dysmenorrhea: a systematic review and meta-analysis. Current Drug Research Reviews. 2024;16(2):219-227.
- Kim J, Noh W, Kim A, et al. The effect of fenugreek in type 2 diabetes and prediabetes: a systematic review and meta-analysis of randomized controlled trials. International Journal of Molecular Sciences. 2023;24(18):13999.
- Ouzir M, El Bairi K, Amzazi S. Toxicological properties of fenugreek (Trigonella foenum graecum). Food and Chemical Toxicology. 2016;96:145-154.
- Shabil M, Bushi G, Bodige PK, et al. Effect of fenugreek on hyperglycemia: a systematic review and meta-analysis. Medicina (Kaunas). 2023;59(2):248.
- Visuvanathan T, Than LTL, Stanslas J, et al. Revisiting Trigonella foenum-graecum L.: pharmacology and therapeutic potentialities. Plants (Basel). 2022;11(11):1450.
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