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NCCIH Clinical Digest

for health professionals

The NCCIH Clinical Digest is a monthly e-newsletter that summarizes the state of the science on complementary and integrative health practices for a health condition (diabetes, cancer, sleep disorders, etc.)—clinical guidelines, literature searches, continuing medical education, and information for patients.

In each issue, you'll find evidence-based information for several complementary health practices used for the highlighted condition.

If a friend or colleague has directed you to this resource, we encourage you to subscribe to NCCIH Clinical Digest.

Herb-Drug Interactions

December 2024image of hands holding a medicine bottle

The possibilities of drug interactions, direct toxicities, and contamination with active pharmaceutical agents are among the safety concerns about dietary and herbal supplements. Although there is a widespread public perception that herbs and botanical products in dietary supplements are safe, research has demonstrated that these products carry the same dangers as other pharmacologically active compounds. Interactions may occur between prescription drugs, over-the-counter drugs, dietary supplements, and even small molecules in food—making it a daunting challenge to identify all interactions that are of clinical concern.

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