National Center for Complementary and Integrative Health (NCCIH)

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St. John's Wort

St. John's wort is a plant with yellow flowers whose medicinal uses were first recorded in ancient Greece. The flowering tops of St. John's wort are used to prepare teas, tablets, and capsules containing concentrated extracts. Liquid extracts and topical preparations are also used. St. John’s wort interacts with many medications, making the medications less effective.